ROMBIOMEDICA - Medical Devices' Importer

XELMA - Biological Treatment for Hard-To-Heal Wounds

Xelma is a novel tratment for hard-to-heal wounds, primarly venous leg ulcers. Xelma provides a temporary extracellular matrix protein for cell attachment. This biological treatment approach is novel because it is designed to restore the balance by replacing crucial components of the defective extracellular matrix. In clinical investigations Xelma has shown promising benefits in hard-to-heal wounds.

The enclosed photographs prove this thing, by showing how the wound heals while being treated with Xelma (days 0, 3, 7 and 10 of treatment). The photographs were taken by Dr Bogdan Marinescu (Central Military Emergency Hospital "Dr. Carol Davila Bucharest"), while he was researching in October 2008 for a study on wound management.

Xelma is a sterile ready-to-use product for topical application. Xelma consists of extracellular matrix proteins (amelogenins) in a viscous water solution of propylene glycol alginate.

Initiates wound healing in hard-to-heal wounds
Functions as a temporary matrix for cell attachment
Is easy to handle

This is how Xelma works:

When applied to the wound bed Xelma provides a temporary extracellular matrix protein for cell attachment. This created favourable conditions for wound healing by restoring vital cell functions including proliferation, migration and production of growth factors and essential extracellular matrix components. Restoration of the cellular and biochemical balance is thereby facilitated in the hard-to-heal wound, which will promote wound healing.

Area of use:

Xelma is indicated for hard-to-heal ulcers, primarly venous leg ulcers. Xelma can be used under compression therapy.